Medicine

Preclinical Medicine Books

  • WWWM
    • £4.99
    • RRP £12.99
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    If you have an ailment or illness and want to identify it quickly while at home, this is the guide for you.

    It has an easy-to-follow, visual symptom checker that will help you recognise the symptoms of what might be wrong and what you should do.

    The head-to-toe visual diagnostic guides will also help you recognise situations that are urgent or potentially life-threatening.
  • BEMRS
    Melvin I. Simon
    • £116.00
    • RRP £145.00
    • Save £29.00
    In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. Biothermodynamics, Part C presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an "energy book-keeping system." While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well.
  • BIRGZ
    Novartis Foundation
    • £96.00
    • RRP £120.00
    • Save £24.00
    The past decade has seen mounting global concern regarding viral outbreaks such as SARS, avian influenza and West Nile virus. In 2004 and 2005, reports of bird-to-human, and possible human-to-human, transmissions of the H5N1 influenza viruses raised fears that these viruses could cause a pandemic on the scale of the Spanish flu pandemic of 1918. Previous to this, a novel coronavirus had been identified as the aetiological agent of the severe acute respiratory syndrome (SARS), a new respiratory viral disease that emerged at the end of 2002 and caused profound disturbances in over 30 countries worldwide in 2003. It is not known whether the SARS coronavirus will re-emerge, especially since its origins and potential reservoir(s) are unresolved. However, these outbreaks have shown that these viruses can emerge in any part of the world at any time. This book critically evaluates the latest scientific evidence on novel or re-emerging viral diseases and brings together contributions from world experts on this topic, explaining best practice in their area, and discussing lessons learned and how best to collaborate to prevent and control future outbreaks. Topics covered include:* the latest advances in virology, particularly in the area of epidemiology* diagnostics* animal models for viral infection* antiviral and vaccine development Novel and Re-emerging Respiratory Viral Diseases offers a comprehensive and interdisciplinary account of all aspects of the topic, from basic molecular biology to public health issues, and is therefore essential reading for virologists, infectious disease specialists, public health managers, researchers and epidemiologists, as well as those working in vaccine development, pharmaceutical medicine and drug discovery
  • BEKHP
    Klaas Roelof Westerterp
    • £39.99
    • RRP £49.99
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    Energy balance can be maintained by adapting energy intake to changes in energy expenditure and vice versa, where short-term changes in energy expenditure are mainly caused by physical activity. Questions are whether physical activity is affected by over and under-eating, is intake affected by an increase or a decrease in physical activity, and does overweight affect physical activity? Presented evidence is largely based on studies where physical activity is quantified with doubly labeled water. Overeating does not affect physical activity while under-eating decreases habitual or voluntary physical activity. Thus, it is easier to gain weight than to lose weight. An exercise induced increase in energy requirement is compensated by intake while a change to a more sedentary routine does not induce an equivalent reduction of intake and generally results in weight gain. Overweight and obese subjects have similar activity energy expenditures than lean people despite they move less. There are two options to reverse the general population trend for an increasing body weight, reducing intake or increasing physical activity. Based on the results presented, eating less is most effective for preventing weight gain, despite a potential negative effect on physical activity when reaching a negative energy balance.
  • BEJOZ
    Daron Smith
    • £38.39
    • RRP £47.99
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    Research in Clinical Practice is a neat, pocket-sized reference guide examining how to get the most from actively participating in research. Including how to begin, avoiding pitfalls, whom to approach and what questions to ask - all significant practicalities for conducting research in the reader's area of interest. Each reader will learn how to make the best use of such a valuable time. Written by two experienced surgeons, both of whom achieved post graduate research degrees, Research in Clinical Practice, is an essential tool for clinicians embarking on a research project as well as those who are new to supervising researchers.
  • AITYR
    Jennifer D. Berton
    • £28.79
    • RRP £35.99
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    Providing up-to-date and comprehensive information, this practical guide uses clinical case examples and professional codes of ethics to help addiction counselors learn and apply ethical standards. Real-life examples of ethical dilemmas in clinical practice illustrate potential pitfalls and the actions needed when faced with a dilemma.Since most ethical decisions are not clear cut,the authorexplores the grey area of each dilemma and provides guidelines on how to determine the best course of action when the best course is unclear. This book emphasizes ethics as a set of guidelines aimed at protecting the client, the clinician, and the profession as a whole.
  • BMLQQ
    Marie-Neige Cordonnier
    • £21.59
    • RRP £26.99
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    French biologist and chemist Louis Pasteur (1822-1895) transformed medicine-and the lives of people around the world-when he developed the first rabies vaccine in 1885. Two years later, he founded the Institut Pasteur to fight infectious diseases-tuberculosis, hepatitis, tetanus, plague, influenza, and many more. For 130 years, this international organization has been at the forefront of revolutionary discoveries that have contributed enormously to major advances in medicine, in particular the isolation of HIV in 1983. With 33research units in Paris, 33 Institutes throughout the world, and 10 Nobel Prizes, the Institute has truly changed the world. This detailed, illustrated, and fully documented book sheds light on the activities and battles the Institute has led throughout its history, and its plans for the future.
  • BLZLI
    Ed Park
    • £16.40
    • RRP £20.50
    • Save £4.10
    What if everything you think you know about getting older and staying healthy is . . . wrong? In The Telomere Miracle, Dr. Ed Park explores the revolutionary idea that disease and aging in humans all arises from one single source: genetic errors caused by shortening of telomeres, or the sequences of DNA at the ends of our chromosomes. Telomeres naturally shorten over time, and ultimately, as a result, our whole body deteriorates, leading to a range of ailments-including many we associate with aging, from diabetes to hypertension to macular degeneration to cancer. But as Dr. Park explains, instead of a thousand different diseases, we're really confronting one disease with a thousand faces. And we have the ability to slow down the process-or even turn it around and effectively turn back the clock. In these pages, Dr. Park conveys cutting-edge science in a lively style, using illustrations and metaphors ranging from auto parts to superheroes that everyone can relate to. Then he shows you how you can intervene in the aging process through practices and techniques that boost the activity of the enzyme telomerase-the body's internal fountain of youth on a cellular level. "The simple yet profound message you'll find here," Dr. Park writes, "is that inside your cells, your body already has the necessary tools to repair itself and to stay young forever."
  • BLMYT
    Gina Kolata
    • £16.00
    • RRP £20.00
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    The phone rings; the doctor has the results. "Are you ready Amanda?" The two people Amanda Baxley loves the most had begged her not to be tested. But she had to find out. If your family carried a mutated gene that foretold brutal illness and you could find out if you inherited it, would you do it? Would you confront it, accepting whatever answer came? Or ignore it while you could? In Mercies in Disguise, acclaimed New York Times reporter and bestselling author Gina Kolata tells the story of the Baxleys, an upstanding family in small town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally, they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile, science, progressing for 50 years along a parallel track, handed the Baxleys a question--not a cure, but a blood test that would reveal who had the gene for the disease. Science offered another dilemma--fertility specialists had created a way to spare the children. A work of narrative nonfiction in the tradition of the The Immortal Life of Henrietta Lacks, Mercies in Disguise tells the story of a family that took matters into its own hands when medicine could not help. It's a story of a family dealing with unspeakable tragedy without being driven apart. It is the story of a young woman--Amanda Baxley--who faced the future, determined to find a way to disrupt her destiny.
  • AJADW
    Dorothy H. Crawford
    • £13.59
    • RRP £16.99
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    The Epstein-Barr virus (EBV) was discovered in 1964. At the time, the very idea of a virus underlying a cancer was revolutionary. Cancer is, after all, not catching. Even now, the idea of a virus causing cancer surprises many people. But Epstein-Barr, named after its discoverers, Sir Anthony Epstein and Dr Yvonne Barr, is fascinating for other reasons too. Almost everyone carries it, yet it is only under certain circumstances that it produces disease. It has been associated with different, apparently unrelated, diseases in different populations: Burkitt's Lymphoma, producing tumours in the jaw, in African children; a nasal tumour in China; glandular fever in Europe and the USA; and the majority of cases of Hodgkin's Disease everywhere. This book tells the story of the discovery of the virus, and the recognition of its connection with these various diseases - an account that spans the world and involves some remarkable characters and individual stories.
  • AZOYD
    Sharad P. Paul
    • £13.59
    • RRP £16.99
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    Take charge of your health by understanding the connection between our evolutionary past and our future wellbeing with this practical guide to personalized health and nutrition-from distinguished physician Dr. Sharad Paul. Recognized as one of the best in his field, surgeon, academic, and philanthropist, Dr. Sharad Paul combines everyday health with evolutionary biology and explains how to improve your overall wellness by following a diet and exercise plan according to your gene type. Starting with our brains, this book covers everything from skin and muscles, to hearts, diets, and stress management. Throughout, Dr. Paul shares key information and provides steps to improve our daily wellbeing-impacting everything from our energy levels to memory retention to our overall longevity. Our evolutionary past and genetic makeup determine how and why the body works the way it does and how it all combines to make us unique individuals. Presenting a compelling blend of medical mysteries, patient stories, and science, Dr. Paul has developed a revolutionary approach to wellness that will result in beautiful skin at any age, a healthier diet for muscle endurance and skeletal strength, a more resilient and efficient heart, better mood and memory balance, and more.
  • BPNEW
    Peter Dorward
    • £13.59
    • RRP £16.99
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    Everyone is a patient sooner or later. Almost everyone has some experience of being misunderstood by doctors; encounters with difficult doctors; of relationships burdened with mutual bafflement, hostility and pain. Every doctor is haunted by memories of difficult relationships with patients, of the decisions made, and the outcomes that followed. People whom, despite all of their patience, persistence, the best communication, diagnostic and reasoning skills, they haven't helped. People for whose unique suffering it seems medicine has nothing to offer. Dr. Peter Dorward explores the many ethical dilemmas that GPs must face every day, to explain why it is that despite vast resources, time, skill and dedication, medicine is so often destined to fail. His recollections include his worst failures and biggest challenges, ranging from the everyday, the tragic, the grotesque, the villainous and the humorous. The Human Kind presents a fresh understanding of the difficult relationship between doctor and patient, and the challenges which both must face.
  • BBHTI
    • £8.76
    • RRP £10.99
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    The scandals of poor care and repeated cover-ups in the NHS in recent years have raised serious questions about the mistreatment of NHS whistleblowers. This book is autobiographical and offers the first detailed account of the ruin of a highly competent senior doctor who blew the whistle. Dr David Drew was a NHS consultant at Walsall Manor Hospital for over 19 years, including 7 spent as head of the paediatric department, before ongoing concerns over the state of poor care led him to become a whistleblower. This put him on a collision course with senior NHS hospital managers. Removed as head of department, he was suspended on trumped up charges, faced allegations of mental illness and disciplinary action and was dismissed for Gross Misconduct and Insubordination. David's eye-opening account gives a unique insight into the NHS procedures that are used to dispose of senior management's critics - at the cost of patient care.
  • BLOID
    Kat Arney
    • £7.99
    • RRP £9.99
    • Save £2.00
    The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work? There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the `recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. Figuring out how it all works - how your genes build your body - is a major challenge for researchers around the world. And what they're discovering is that far from genes being a fixed, deterministic blueprint, things are much more random and wobbly than anyone expected. Drawing on stories ranging from six toed cats and stickleback hips to Mickey Mouse mice and zombie genes - told by researchers working at the cutting edge of genetics - Kat Arney explores the mysteries in our genomes with clarity, flair and wit, creating a companion reader to the book of life itself.
  • BGKQL
    Rachel Clarke
    • £14.99
    • RRP £16.99
    • Save £2.00
    To be a medical novice who makes decisions which - if you get them wrong - might forever alter, or end, a person's life? To toughen up the hard way, through repeated exposure to life-and-death situations, clinging on until your skills, expertise and the thickness of your skin are finally a match for them? Now frame these questions in the context of a health service so overstretched and understaffed that its doctors and nurses feel every day as though they are scrabbling against the odds just to keep their patients safe. In this heartfelt, deeply personal account of life as a junior doctor in today's health service, former television journalist turned doctor, Rachel Clarke, captures the extraordinary realities of ordinary life on the NHS front line. From the historic junior doctor strikes of 2016 to the 'humanitarian crisis' declared by the Red Cross, the overstretched health service is on the precipice, calling for junior doctors to draw on extraordinary reserves of what compelled them into medicine in the first place - and the value the NHS can least afford to lose - kindness.Your Life In My Hands is at once a powerful polemic on the systematic degradation of Britain's most vital public institution, and a love letter of optimism and hope to that same health service and those who support it. This extraordinary memoir offers a glimpse into a life spent between the operating room and the bedside, the mortuary and the doctors' mess, telling powerful truths about today's NHS frontline, and capturing with tenderness and humanity the highs and lows of a new doctor's first steps onto the wards in the context of a health service at breaking point - and what it means to be entrusted with carrying another's life in your hands.
  • AVKNG
    Samer A. M. Nashef, FRCS
    • £7.19
    • RRP £8.99
    • Save £1.80
    As a medical student, Samer Nashef was unofficially blacklisted when he started asking questions about the death rates of more senior surgeons. Since then, he has made his name challenging colleagues to be more open and accurate about the success of the procedures they perform. In The Naked Surgeon, Nashef unclothes his own profession, offering an unprecedented and often controversial view inside the operating theatre. He explains how surgeons can 'game' the system to make their results appear better; why the way a surgeon ties the knot in a single stitch could make a life-or-death difference; and why patients operated on the day before a surgeon goes on holiday are twice as likely to die than those operated on during that surgeon's first day back. Full of eye-opening revelations about the cardiac surgeon's craft, The Naked Surgeon is necessary reading for anybody considering medical intervention now, or in the future.
  • AVHZM
    Deepak Chopra, M.D.
    • £7.19
    • RRP £8.99
    • Save £1.80
    "You are not simply the sum output of your genome," write Deepak Chopra and Rudy Tanzi, Director of the Genetics and Aging Research Unit at Massachusetts General Hospital. "You are the user and inventor of your genome." For years it was accepted knowledge that genes were fixed components of our bodies, and that we as individuals were incapable of altering our genetic make-up. Yet groundbreaking research suggests that changes in lifestyle and diet can greatly influence our genetic predispositions to disease and certain physical and psychological behaviours. Moreover, the adoption of ancient Vedic practices such as yoga and meditation can create genetic mutations that allow us to lead longer and healthier lives. Super Genes includes meditation and breathing practical exercises, as well as information on how to manage risk factors for disease. Combining scientific research with insights from ancient traditions, Chopra and Tanzi show how we need not be at the mercy of our genetic inheritance. Instead, they argue, we have the power to rewire our super genes for health and happiness.
  • AVJGN
    Deepak Chopra, M.D.
    • £7.19
    • RRP £8.99
    • Save £1.80
    "You are not simply the sum output of your genome," write Deepak Chopra and Rudy Tanzi, Director of the Genetics and Aging Research Unit at Massachusetts General Hospital. "You are the user and inventor of your genome." For years it was accepted knowledge that genes were fixed components of our bodies, and that we as individuals were incapable of altering our genetic make-up. Yet groundbreaking research suggests that changes in lifestyle and diet can greatly influence our genetic predispositions to disease and certain physical and psychological behaviours. Moreover, the adoption of ancient Vedic practices such as yoga and meditation can create genetic mutations that allow us to lead longer and healthier lives. Super Genes includes meditation and breathing practical exercises, as well as information on how to manage risk factors for disease. Combining scientific research with insights from ancient traditions, Chopra and Tanzi show how we need not be at the mercy of our genetic inheritance. Instead, they argue, we have the power to rewire our super genes for health and happiness.
  • ADQVF
    Jonathan Slack
    • £6.39
    • RRP £7.99
    • Save £1.60
    The topic of stem cells has been very high profile in the media in recent years. There is much public interest in stem cells but also much confusion and misinformation, with some companies already offering 'stem cell products' and bogus 'stem cell therapies'. In this Very Short Introduction, Jonathan Slack introduces stem cells; what they are, what scientists do with them, what stem cell therapies are available today, and how they might be used in future. Despite important advances, clinical applications of stem cells are still in their infancy. Most real stem cell therapy today is some form of bone marrow transplantation. Slack introduces stem cells by explaining the difference between embryonic stem cells, which exist only in laboratory cultures, and tissue-specific stem cells, which exist in our bodies. Embryonic stem cells can become any cell type in the body, so diseases that may in future be treated by functional cells derived from these sorts of stem cell include diabetes, Parkinson's disease, heart disease, and spinal trauma. He then goes on to discuss the properties of tissue-specific stem cells and the important technique of bone marrow transplantation. Slack concludes by analysing how medical innovation has occurred in this area in the past, and draws out some of the lessons for the development of new therapies in the future.
  • AQQTM
    Robynne Chutkan
    • £13.69
    • RRP £14.99
    • Save £1.30
    The author of Gutbliss and one of today's preeminent gastroenterologists distils the latest research on the microbiome into a practical program for boosting overall health. The microbiome - the collective name for the trillions of bacteria that live in our gut - is today's hottest medical topic. Synthesising the latest findings, Dr Robynne Chutkan explains how the standard Western diet and lifestyle are starving our microbiome, depleting the 'good bugs' that keep us healthy, and encouraging overgrowth of exactly the wrong type of bacteria. The resulting imbalance makes us more prone to disease and obesity, and negatively affects our cravings, our immunity, and even our genes. But beyond the science, what sets The Microbiome Solution apart is Dr Chutkan's powerful plan for optimising your wellbeing. Discover how our hyper-hygienic lifestyle, enforced with hand-sanitising gels and antibiotics, is stripping our bodies of their natural protective systems; learn about essential prebiotics and probiotics; read a private introduction to the stool transplant, the radical super-fix for a severe microbial imbalance; and cook for thousands of billions with recipes that replenish your microbiome. This book will bring welcome relief to the many millions worldwide who need to grow a good 'gut garden' - and enjoy healthier, happier lives.
  • BAOKS
    Kenneth Stoller
    • £16.89
    • RRP £17.99
    • Save £1.10
    In Incurable Me, a maverick physician brings transparency to some of medicine's most closely guarded secrets. As he establishes a link between commerce and medical research, K. P. Stoller also explains how to treat some of the most worrisome diseases and conditions afflicting humans today--including Lyme disease, brain trauma, dementia, and autism. Dr. Stoller maintains that the best evidence in medical research is not incorporated into clinical practice unless the medical cartel has the potential to make large amounts of money promoting the results of the research. Stoller takes his provocative argument a step further, maintaining that if specific research conflicts with a powerful entity's financial interests, the likely result will be an effort to suppress or distort the results. Stoller cites numerous examples, including corporate influence on GMO labeling and public health. Stoller also explores how "revolving-door-employment" between the Centers for Disease Control and large pharmaceutical companies can affect research results--as well as our health. Written in an accessible style that is thoroughly appropriate for a lay audience, Incurable Me is a must-read for anyone interested in the state of modern medicine.
  • ASMQP
    • £33.99
    • RRP £34.99
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    This classic textbook has provided students of medical law and ethics with a framework for exploring this fascinating subject for over 30 years. Providing coverage of all of the topics found on medical law courses, it gives an overview of the inter-relationship between ethical medical practice and the law. Medical law is significantly shaped by the courts, and as such this book provides extensive coverage of recent judicial decisions as well as statutory developments. This book has continually evolved to reflect changes in the law and shifting ethical opinions and the tenth edition continues to fulfil this remit.
  • BPKNP
    Henry Marsh
    • £8.09
    • RRP £8.99
    • Save £0.90
    THE SUNDAY TIMES NO.1 BESTSELLER Henry Marsh has spent four decades operating on the human brain. In this searing and provocative memoir following his retirement from the NHS, he reflects on the experiences that have shaped his career and life, gaining a deeper understanding of what matters to us all in the end.
  • AKUER
    Daniel M. Davis
    • £9.69
    • RRP £9.99
    • Save £0.30
    In The Compatibility Gene, leading scientist Daniel M Davis tells the story of the crucial genes that define our relationships, our health and our individuality. We each possess a similar set of around 25,000 human genes. Yet a tiny, distinctive cluster of these genes plays a disproportionately large part in how our bodies work. These few genes, argues Davis, hold the key to who we are as individuals and our relationship to the world: how we combat disease, how our brains are wired, how attractive we are, even how likely we are to reproduce. The Compatibility Gene follows the remarkable history of these genes' discovery. From the British scientific pioneers who struggled to understand the mysteries of transplants to the Swiss zoologist who devised a new method of assessing potential couples' compatibility based on the smell of worn T-shirts, Davis traces a true scientific revolution in our understanding of the human body: a global adventure spanning some sixty years. "Unusual results, astonishing implications and ethical dilemmas". (The Times). "Packed with an insider's knowledge". (New York Times). "He makes immunology as fascinating to popular science readers as cosmology, consciousness, and evolution". (Steven Pinker). "An elegantly written, unexpectedly gripping account". (Bill Bryson Guardian, Books of the Year). Daniel M Davis is director of research at the University of Manchester's Collaborative Centre for Inflammation Research and a visiting professor at Imperial College, London. He has published over 100 academic articles, including papers in Nature and Science, and Scientific American. He has won the Oxford University Press Science Writing Prize and given numerous interviews for national and international media. He was elected a Fellow of the Academy of Medical Sciences in 2011.